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Gene Machine: The Race to Decipher the Secrets of the Ribosome
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.” https://t.co/gYrdFFcD4T
Mercer_Pub 248
The study describes the development of a continuous evolution system to engineer small degron tags that can be inserted into endogenous genes and selectively degrade proteins using specific small molecules.
Link
A Crack In Creation: Gene Editing and the Unthinkable Power to Control Evolution
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Researchers also quickly discovered that the virus’s uncanny ability to bind with the ACE-2 receptor was no accident. To merge with human cells, the spike needed to change shape from a “pre-fusion” to a “post-fusion” structure. But the spike protein couldn’t change its shape on its own. It needed help from an outside source, a human enzyme called f
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