Sublime

The study describes the development of a continuous evolution system to engineer small degron tags that can be inserted into endogenous genes and selectively degrade proteins using specific small molecules.

DeepSeek-R1 enhances reasoning capabilities in large language models through innovative reinforcement learning techniques, outperforming prior models while addressing challenges like readability, language mixing, and distillation for smaller models.

DeepSeek-R1 introduces two large language models, DeepSeek-R1-Zero and DeepSeek-R1, utilizing reinforcement learning for enhanced reasoning capabilities without supervised fine-tuning, along with distillation techniques for smaller models.