Sunday Signal: Google DeepMind announces AlphaFold 3, a $1.3 billion exit and reaching critical mass

Focus is a force multiplier on work.

Almost everyone I’ve ever met would be well-served by spending more time thinking about what to focus on. It is much more important to work on the right thing than it is to work many hours. Most people waste most of their time on stuff that doesn’t matter.

Once you have figured out what to do, be unstoppable about... See more

Don’t divide your attention: focusing on one thing yields increasing returns for each unit of effort.

At a micro level, an extra hour of focus on the current project has a much higher return than an hour on something new, or worse, 5 minutes each on 12 new things. Before you ever do something new, you should understand the opportunity cost vs. exis... See more

If you look around, you’ll notice the people and organizations moving the fastest are the focused ones. Not only do they focus on a few ideas, but within the scope of those ideas, they are able to focus on the key variables.

Identifying the variables that matter comes with focus. When you commit to living in a problem, you understand things about i... See more

"Be ruthless about what you ignore. Time, energy, and resources are so precious. You have to be ferocious about cutting your priorities—more than you realize and certainly more than is comfortable.

You can only deeply commit to a few things. One or two? Maybe three?

Every pretty good, sorta nice, kinda fun thing you abandon is like shedding a weight... See more